Solutions
Single cell, AI-driven, lab-on-a-chip technology to accelerate the development of new therapies
We measure each cell's fate and performance individually to determine which drug performs best.
"How does my therapy perform over time?"
We can monitor the dynamics of the effect of your treatment in your favourite experimental system over time.
Explore the details
Our platform is cell and therapy agnostic. It can map the effects of various types of therapeutic modality – including engineered T cell, antibodies, engagers, small molecules – on virtually any type of target cell.
"How are my cells moving and interacting among each other?"
We can track the motility of the cells and their contacts with any other cell in the system over time.
Explore the details
Our AI-based analysis can reconstruct the map of cell trajectories, cell-cell interactions and target cell engagement during time. We will reveal how each cell moves, the types of interactions it engages in, and precisely measure which cells exhibit the expected phenotype in response to the therapy under investigation.
"Can I measure the fate and performance of each cell individually?"
We can measure the dynamics and the therapeutic efficacy of each cell in your experimental system.
Explore the details
Digi.Bio’s platform allows you to investigate the efficacy and the heterogeneity of the therapy.
For example, we can highlight the heterogeneity in therapy responses within the intended target populations or, in the case of cell-based therapies, visualize (sub)populations of cells exhibiting (serial) killing activity against their targets.
Additionally, we can correlate these parameters with other key features, such as motility and target engagement.
High-Content Analysis, Deeper Insights
Track, analyze, and compare cytotoxicity data in real time to identify the best performing drugs.
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Cell Classification
- Stained & label-free cell type identification
- Stained & label-free viability assessment
Analysis & Tracking
- Cell motility and tracking
- Cell-cell interaction kinetics
- Serial killing analysis
Key Capabilities
Effortless Cytotoxicity Testing
Test therapies for cytotoxicity over time—fully automated, no operator needed.

Automated digital microfluidics enables precise comparisons across multiple conditions, ensuring high reproducibility and quality data.
Our vision
A future where groundbreaking therapies reach everyone, eradicating every disease — because no one should be left behind.
Our mission
Digi.Bio's mission is to accelerate life-saving therapies, making them safer and more precise through single-cell profiling technology.


Federico Muffatto
Founder & CEO
Federico Muffatto is a scientist-turned-entrepreneur dedicated to engineering biology for the future of medicine. His journey started at age five when he vowed to find a cure for his grandfather’s Parkinson’s disease. This passion led him into bioengineering, where he explored the intersection of biology and technology. After his studies, he worked in the biotech industry, focusing on cell reprogramming and synthetic biology. It was during this time that he encountered the real challenge: engineering living cells is hard, and better tools are needed to do it at scale.
Driven by this insight, Federico founded Digi.Bio, a company bridging the digital and biological worlds to advance cell-based therapies. Initially, he led the development of EWOD microfluidics and worked hands-on in R&D. Today, he focuses on computational approaches and business development, helping bring precision, automation, and AI-driven insights to drug development. Digi.Bio’s mission is to accelerate life-saving immune therapies, making them safer and more precise through single-cell immune profiling technology.
Outside of biotech, Federico enjoys walking in nature, growing plants and breeding animals, cooking (especially molecular cuisine), and diving into philosophy—all driven by the same curiosity that fuels his work.

Simone Dalla Vecchia
Head of Technology
Simone Dalla Vecchia is an experienced TechBio and Biotech leader with 10+ years of expertise spanning biotechnology, molecular biology, bioinformatics, analytical chemistry, spectroscopy, image analysis, microfluidics, automation, and prototype development for life sciences.
As Head of Technology at Digi.Bio, he drives hardware integration and assay development, ensuring seamless innovation. Previously, he conducted research at the University of Padua, where he earned a Master’s in Industrial Biotechnology with a focus on Nanotechnology, laying the groundwork for his expertise in electronics and product development for life sciences.
With a blend of academic depth and industry expertise, Simone is a key innovator in biotechnology.”

Andrea Bisso
Head of Immunotherapy
Andrea Bisso, Ph.D., is a biotech leader with two decades of expertise in oncology, immunology, and cell therapy.
As Head of Immunotherapy at Digi.Bio, he drives strategic partnerships to advance immunotherapy innovation.
He is also the founder of ABixThera, a consulting firm supporting next-generation therapies.
Previously, he led tumor-specific γδTCR cell therapy development at Gadeta BV. His background includes a Ph.D. in Molecular Medicine, postdoctoral research in cancer genetics, high-impact publications, and a co-invented patent.
A devoted Inter Milan fan, tennis and F1 enthusiast, and passionate pizza and gelato maker, Andrea applies the same dedication to science as he does to crafting the perfect dough and scoop.”

Danio Cionini
Data Scientist
Danio Cionini, is a data scientist at Digi.Bio. With a background in signal processing, a passion for newest technologies and innovation, he moved from Italy in search of opportunities to contribute in the battle against cancer.
His role is to develop state-of-the-art methodologies and innovate existing technologies to improve the quality and relevance of biological data.
A huge Formula1 and A.S Roma fan with a deep motivation in improving his chess craft, he takes every opportunity to learn and experience.”

Adrian Garcia-Martinez
Application Scientist
Adrian Garcia-Martinez moved to the Netherlands directly from Mexico in search of adventure and exciting opportunities in scientific research. He studied a Master’s in Biotechnology at Wageningen University & Research and joined Digi.Bio as an intern just before graduating. His dedication and attitude aligned perfectly with the company’s culture of hard work and commitment. After over two years, he has contributed to application development and manages the laboratory where R&D and assay execution take place.
Digi.Bio’s multidisciplinary environment has allowed Adrian to expand his knowledge into areas such as software and hardware.
In his free time, he enjoys outdoor activities and is always on the lookout for new experiences while exploring nature or the vibrant city of Amsterdam.

Anh Nguyen
Computational Biologist Intern
Anh Nguyen is a young computational biologist with a background and passion in cell and molecular biology. Growing up in Hanoi, Vietnam, she moved to the US for a Bachelor’s degree in Life Sciences and now to The Netherlands for a Master’s degree in Medical Biology.
At Digi.Bio, she leverages the company’s cutting-edge platform to extract and analyze single-cell data, with a focus on investigating the complex interactions between immune cells and tumor cells. Her research focuses on the dynamics of cell motility, cell-cell contact, and tumor cell killing, aiming to uncover insights that could inform cancer immunotherapy strategies.
In her free time, Anh loves reading fantasy books, watching anime, cooking, and cafe-hopping.

Yue Bai
Data Science Intern
Yue Bai is a Data Science Intern at Digi.Bio. She has a BSc in Biotechnology, which laid a strong foundation in the life sciences and sparked her passion for bioinformatics and data science. She then pursued a Master’s in Bioinformatics at UvA and VU, using her interdisciplinary background to tackle complex biological challenges.
Motivated by a deep interest in immunotherapy, Yue is working on her Master Thesis at Digi.Bio, where she analyzes tumor-effector cell interactions from both algorithmic and biological perspectives. Her project aims to improve single-cell movement tracking and trajectory analysis, providing better insights into cellular behavior and immune response.
Outside of her academic pursuits, Yue enjoys an active lifestyle and exploring the outdoors, always seeking new adventures.

Felicia Iordachi
Data Science Intern
Felicia Iordachi is a data science intern at Digi.Bio and an incoming student at the University of Pennsylvania, currently on a gap year.
Prior to joining Digi.Bio, Felicia’s journey in bioinformatics has included experiences both in her home country, Moldova, and in California, USA, where she worked primarily in immunogenomics, RNA-Seq, and methylation studies. Her research has been featured at major science competitions and events like Regeneron’s ISEF and the UN General Assembly Science Summit.
At Digi.Bio, she’s thrilled to contribute to innovative cancer immunotherapy strategies while continuing to grow with the team.
Outside the lab, Felicia loves to redirect her creativity towards painting, practicing music, or enthusiastically attempting (and usually failing at) a bunch of outdoor sports.

Tommaso Delaini
Operations
Tommaso joined Digi.Bio in 2022, diving into the company’s operations sector with little prior experience but a strong drive to learn and grow. Embracing the fast-paced environment, he eagerly takes on new opportunities and challenges.
In his role, he collaborates closely with company management to ensure seamless operations and effective internal control.
A passionate metal music fan, Tommaso brings the same energy and enthusiasm to his work every day.”
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